Studies of protein folding on membranes and in crowded environments and bridging the research-teaching gap in K-12 science

Proteins;Protein Folding;Crowding;Science Education;Science Outreach;Membrane Proteins;Peptide Design

Denos, Sharlene

关键词: Proteins;    Protein Folding;    Crowding;    Science Education;    Science Outreach;    Membrane Proteins;    Peptide Design;   

Others  :  https://www.ideals.illinois.edu/bitstream/handle/2142/14567/1_Denos_Sharlene.pdf?sequence=3&isAllowed=y

美国|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

This work deals with three important problems in membrane protein folding studies, namely the preparation and storage of homogeneous small unilamellar vesicles (SUV), the development of an algorithm for selecting soluble trans-membrane helices from known membrane proteins, and the characterization of membrane binding of single surface and trans-membrane helices.I then describe the effects of excluded volume on the stability and kinetics of a stable Lambda Repressor mutant Y22WQ33YA3749G.Finally, I discuss two education projects that aim to bridge the gap between scientific research and K-12 teaching.