A novel family of small proteins that affect plant development

Walker, John Charles

University of Missouri--Columbia. Curators.

关键词: 99 General And Miscellaneous//Mathematics, Computing, And Information Science;    Genes;    59 Basic Biological Sciences;    Proteins;    Hypothesis;   

DOI  :  10.2172/1013061
RP-ID  :  Final Reports
RP-ID  :  FG02-05ER15652
RP-ID  :  1013061

美国|英语

来源: UNT Digital Library

【 摘 要 】

The DVL genes represent a new group of plant proteins that influence plant growth and development. Overexpression of DVL1, and other members of the DVL family, causes striking phenotypic changes. The DVL proteins share sequence homology in their C-terminal half. Point mutations in the C-terminal domain show it is necessary and deletion studies demonstrate the C-terminal domain is sufficient to confer the overexpression phenotypes. The phenotypes observed, and the conservation of the protein sequence in the plant kingdom, does suggest the DVL proteins have a role in modulating plant growth and development. Our working hypothesis is the DVL proteins function as regulators of cellular signaling pathways that control growth and development.