Studies towards understanding the function of LanCL1

LanCL1;, , protein-protein interaction;apoptosis;oxidative stress;knockout mouse

Koh, Tong Hee ; van der Donk ; Wilfred A.

关键词: LanCL1;    , , protein-protein interaction;    apoptosis;    oxidative stress;    knockout mouse;   

Others  :  https://www.ideals.illinois.edu/bitstream/handle/2142/31101/Koh_TongHee.pdf?sequence=1&isAllowed=y

美国|英语

来源: The Illinois Digital Environment for Access to Learning and Scholarship

【 摘 要 】

LanC-like protein 1 (LanCL1) is a eukaryotic homolog of bacterial protein LanC. Unlike the well studied LanC proteins, the functions of LanC-like proteins are yet unknown. To investigate the function of LanCL1 several studies were undertaken. Proteins interacting LanCL1 were tried to be found but were not accomplished. Also, the role of LanCL1 in apoptosis and oxidative stress were hypothesized, but the studies indicated no correlation. Finally, LanCL1 knockout mice were generated for further investigation.