This report presents the results of an investigation of the magnitudes and orientations of the in situ stresses in basement rocks beneath the Savannah River Site (SRS). Stress magnitudes were measured using the hydraulic fracturing technique. Stress orientations were obtained from the orientation of stress-induced well bore breakouts and hydraulically-induced fractures. The measurements reported here were carried out in the New Production Reactor (NPR) hole, drilled to a total depth of 4000 feet near the center of the Savannah River Site, at roughly the location of the proposed NPR. The results obtained in this study are compared to previous stress measurements made using the same techniques in a series of shallower holes on the SRS, and discussed in the context of the regional stress field and potential seismic hazard.