Mechanisms underlying the adaptive response against spontaneous neoplastic transformation induced by low doses of low LET radiation - Final Technical Report

Redpath, John Leslie

University of California (System). Regents.

关键词: In Vitro;    Transformations Low Dose Low-Let Radiation, Radiation-Induced Neoplastic Transformation, Dna Repair, Antioxidants;    59 Basic Biological Sciences;    Radiations;    Dna Repair;   

DOI  :  10.2172/897550
RP-ID  :  1
RP-ID  :  FG02-02ER63309
RP-ID  :  897550

美国|英语

来源: UNT Digital Library

【 摘 要 】

The objective of the research was to examine mechanisms underlying the suppressive effects of low doses (<10 cGy) of low-LET radiation on the endpoint of neoplastic transformation in vitro. The findings indicated a role for upregulation of DNA repair but not of antioxidants.