Rapid Nucleic Acid Analysis for Contaminant Impact Evaluation

Chen, Winston C.H.

Oak Ridge National Laboratory

关键词: Dna;    Nucleic Acids;    59 Basic Biological Sciences;    Mutations;    Detection;   

DOI  :  10.2172/839372
RP-ID  :  EMSP-73807--2002
RP-ID  :  839372

美国|英语

来源: UNT Digital Library

【 摘 要 】

The objective of this program is to develop innovative DNA detection technologies to achieve fast mutation screening and to reveal the linkage between gene mutation and contaminants. The specific approach are (1) to develop innovative multiplexing hybridization detection for DNA mutation detection, (2) to develop sequence-proof microarray hybridization technology (3) to develop hybridization on disk and (4) to validate the pollution-mediated mutation can be used for sound risk analysis for setting up the priorities for waste cleanup.