Metal Ion Analysis Using Near-Infrared Dyes and the ''Laboratory-on-a-Chip''

Collins, Greg E. ; Deng, Gang

Naval Research Laboratory, Washington, DC

关键词: Light Sources;    Monitoring;    37 Inorganic, Organic, Physical And Analytical Chemistry;    Deactivation;    Sampling;   

DOI  :  10.2172/835364
RP-ID  :  EMSP-82749-2002
RP-ID  :  FG07-01ER62711
RP-ID  :  835364

美国|英语

来源: UNT Digital Library

【 摘 要 】

The primary research objective of this effort is to develop a portable, capillary electrophoresis microchip capable of sensitively and rapidly monitoring hazardous waste metal ions critical to the successful deactivation and decommissioning (D&D) of contaminated equipment and structures at various DOE sites. Hazardous waste metal ions to be adapted for sensing on the microchip include UO{sub 2}{sup 2+}, Be{sup 2+}, Cr{sup 6+}, Hg{sup 2+}, Pb{sup 2+}, Co{sup 2+}, Ni{sup 2+}, Cs{sup +}, and Sr{sup 2+}. Particular emphasis will be placed on developing viable, new extraction methods for metal ion sampling from both the air via a microimpinger which is integrated onto the microchip itself, and from contaminated surfaces, both techniques being amenable to on-line introduction onto the microchip. Two different detection methods for monitoring the electrophoretic separations taking place down the microchannel will be exploited in this research, indirect and direct detection. Special emphasis will be placed on maintaining the ultimate portability of the final microchip device through the careful selection of metallochromic dyes and fluorophores which are amenable to use of small, inexpensive light sources (e.g., LED's) and photodetectors.