科技报告详细信息
Detection of BCR-ABL Fusion mRNA Using Reverse Transcriptase Loop-mediated Isothermal Amplification | |
Dugan, L C ; Hall, S ; Kohlgruber, A ; Urbin, S ; Torres, C ; Wilson, P | |
关键词: AMPLIFICATION; DETECTION; LEUKEMIA; MYELOID LEUKEMIA; PATIENTS; | |
DOI : 10.2172/1034502 RP-ID : LLNL-TR-520096 PID : OSTI ID: 1034502 Others : TRN: US201204%%46 |
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学科分类:生物科学(综合) | |
美国|英语 | |
来源: SciTech Connect | |
【 摘 要 】
RT-PCR is commonly used for the detection of Bcr-Abl fusion transcripts in patients diagnosed with chronic myelogenous leukemia, CML. Two fusion transcripts predominate in CML, Br-Abl e13a2 and e14a2. They have developed reverse transcriptase isothermal loop-mediated amplification (RT-LAMP) assays to detect these two fusion transcripts along with the normal Bcr transcript.
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RO201704210000170LZ | 2498KB | download |