The cancer genome

Review

关键词: COLORECTAL CANCERS;    HUMAN BREAST;    SOMATIC MUTATIONS;    LUNG-CANCER;    LEUKEMIA;    PATHWAYS;    GENES;    THERAPY;    TUMORS;    SUSCEPTIBILITY;   

DOI  :  10.1038/nature07943

来源: SCIE

【 摘 要 】

All cancers arise as a result of changes that have occurred in the DNA sequence of the genomes of cancer cells. Over the past quarter of a century much has been learnt about these mutations and the abnormal genes that operate in human cancers. We are now, however, moving into an era in which it will be possible to obtain the complete DNA sequence of large numbers of cancer genomes. These studies will provide us with a detailed and comprehensive perspective on how individual cancers have developed.

【 授权许可】

Free