Economic aspects of the association between diabetes and depression: A systematic review

JOURNAL OF AFFECTIVE DISORDERS

卷:142

Review

Molosankwe, Iris^2,3  Patel, Anita^2,3  Jose Gagliardino, Juan⁴  Knapp, Martin^1,2,3  McDaid, David^1,5 

[1] Univ London London Sch Econ & Polit Sci, PSSRU, London WC2A 2AE, England

[2] Kings Coll London, Ctr Econ Mental Hlth, Hlth Serv, London WC2R 2LS, England

[3] Kings Coll London, Populat Res Dept, Inst Psychiat, London WC2R 2LS, England

[4] UNLP Sch Med, CENEXA, Ctr Endocrinol Expt & Aplicada UNLP CONICET La Pl, PAHO WHO Collaborating Ctr Diabet, La Plata, Buenos Aires, Argentina

[5] Univ London London Sch Econ & Polit Sci, European Observ Hlth Syst & Policies, London WC2A 2AE, England

关键词: Costs and cost analysis;    Economics;    Diabetes mellitus;    Depression;    Co-morbidity;   

DOI  :  10.1016/S0165-0327(12)70008-3

来源: Elsevier

【 摘 要 】

Background: The importance of co-morbid diabetes and depression is gaining increased attention. Quantifying the socio-economic and clinical impacts of co-morbidity is important given the high costs of these diseases. This review synthesised evidence on the economic impact of co-morbidity and potential cost-effectiveness of prevention and treatment strategies. Methods: 11 databases from 1980 until June 2011 searched. In addition, websites and reference lists of studies scrutinised and hand search of selected journals performed. Reviewers independently assessed abstracts, with economic data extracted from relevant studies. Results: 62 studies were identified. 47 examined the impact of co-morbidity on health care and other resource utilisation. 11 of these included productivity losses, although none quantified the impact of mortality. Most demonstrated an association between co-morbidity and increasing health service utilisation and cost. Adverse impacts on workforce participation and absenteeism were found. 15 economic evaluations were also identified. Most focused on primary care led collaborative and/or stepped care, suggesting actions may be cost effective. We did not identify any studies looking at actions to reduce the risk of diabetes in people with depression. Limitations: Most studies are set in the US, which may be due to focus on English language databases. Few studies looked at impacts beyond one year or outside the health care system. Conclusion: There is an evidence base demonstrating the adverse economic impacts of co-morbid diabetes and depression and potential for cost effective intervention. This evidence base might be strengthened through modelling studies on cost effectiveness using different time periods, contexts and settings. (C) 2012 Elsevier B. V. All rights reserved.

【 授权许可】

Free