Surgical management of pleomorphic adenoma of parotid gland in elderly patients: Role of morphological features

INTERNATIONAL JOURNAL OF SURGERY

卷:12

Article

Guerra, Germano¹  Testa, Domenico²  Montagnani, Stefania³  Tafuri, Domenico⁴  Salzano, Francesco Antonio⁵  Rocca, Aldo⁶  Amato, Bruno⁶  Salzano, Giovanni⁷  Orabona, Giovanni Dell'Aversana⁷  Piombino, Pasquale²  Motta, Gaetano² 

[1] Univ Molise, Dept Med & Hlth Sci, I-86100 Campobasso, Italy

[2] Univ Naples 2, Otolaryngol Head & Neck Surg Unit, Dept Anesthesiol Surg & Emergency Sci, Naples, Italy

[3] Univ Naples Federico II, Dept Publ Hlth, Naples, Italy

[4] Univ Naples Parthenope, Dept Sport Sci & Wellness, Naples, Italy

[5] Univ Palermo, Dept Surg Oncol & Oral Sci, I-90133 Palermo, Italy

[6] Univ Naples Federico II, Dept Clin Med & Surg, Naples, Italy

[7] Univ Naples Federico II, Dept Neurosci Reprod & Dent Sci, Naples, Italy

关键词: Pleomorphic adenoma;    Parotid gland;    Capsule;    Image analysis software;    Nucleoresection surgical approach;   

DOI  :  10.1016/j.ijsu.2014.08.391

来源: Elsevier

【 摘 要 】

The neoplasms of the salivary glands account for 2% of head and neck tumors and the most common form is the Pleomorphic adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly these tumors occur mostly in females. These benign tumors are composed of epithelial and myoepithelial cells that are arranged with various morphological patterns and subtypes. The classification of these tumors is also based on the amount and nature of the stroma. In literature there is an almost complete consensus that, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called capsule but there is disagreement about the form, extension and thickness of this layer. The treatment is surgical and there are two main different surgical approaches: an enucleation (local dissection) or so-called subtotal superficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristics of PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration, satellite nodules and pseudopodia in the different subtypes are important for the choice of surgical treatment and the first explanation for tumor recurrence. In our study we describe a morphological features of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by a surgical enucleation like method called nucleoresection. (C) 2014 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

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