Alcohol-related liver disease: Areas of consensus, unmet needs and opportunities for further study

JOURNAL OF HEPATOLOGY

卷:70

Review

Thursz, Mark^1,2  Kamath, Patrick S.²  Mathurin, Philippe³  Szabo, Gyongyi⁴  Shah, Vijay H.² 

[1] Imperial Coll, Dept Surg & Canc, Digest Dis Div, London W2 1NY, England

[2] Mayo Clin, Coll Med, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA

[3] Hop Claude Huriez, PU PH, Serv Malad Appareil Digestif, 1er Etage Aile Est,Rue Michel Polonovski, F-59037 Lille, France

[4] Univ Massachusetts, Sch Med, Dept Med, LRB 208,364 Plantat St, Worcester, MA 01605 USA

关键词: ALD;    Alcohol;    Epidemiology;    Endpoints;    Public health;    Unmet needs;    Biomarkers;    Clinical trials;   

DOI  :  10.1016/j.jhep.2018.10.041

来源: Elsevier

【 摘 要 】

A joint meeting of the European Association for the Study of the Liver (EASL) and the American Association for the Study of Liver Diseases (AASLD) was held in London on September 30 and October 1, 2017. The goals of the meeting were to identify areas of broad agreement and disagreement, develop consensus, and determine future directions to ultimately reduce the burden, morbidity, and mortality of alcohol-related liver disease (previously termed alcoholic liver disease). The specific aims of the meeting were to identify unmet needs and areas for future investigation, in order to reduce alcohol consumption, develop markers for diagnosis and prognosis of disease, and create a framework to test novel pharmacological agents with pre-specified treatment endpoints. (C) 2019 European Association for the Study of the Liver and American Association for the Study of Liver Diseases. Published by Elsevier B.V./ Wiley Periodicals, Inc. All rights reserved.

【 授权许可】

Free