The current and future perspectives of zinc oxide nanoparticles in the treatment of diabetes mellitus

LIFE SCIENCES

卷:239

Review

Tang, Kim San^1,2 

[1] Monash Univ Malaysia, Sch Pharm, Jalan Lagoon Selatan, Bandar Sunway 47500, Selangor, Malaysia

[2] Monash Univ Malaysia, Trop Med & Biol Multidisciplinary Platform, Bandar Sunway, Selangor, Malaysia

关键词: Diabetes mellitus;    Hyperglycemia;    Hypoglycemic agents;    Insulin;    Nanoparticles;    Zinc oxide;   

DOI  :  10.1016/j.lfs.2019.117011

来源: Elsevier

【 摘 要 】

Diabetes mellitus (DM) is a multifaceted and costly disease, which requires serious attention. Finding a cheaper anti-diabetic alternative that can act on multiple disease-related targets and pathways is the ultimate treatment goal for DM. Nanotechnology has offered some exciting possibilities in biomedical and drug delivery applications. Zinc oxide nanoparticles (ZnO-NPs), a novel agent to deliver zinc, have great implications in many disease therapies including DM. This review summarizes the pharmacological mechanisms by which ZnO-NPs alleviate DM and diabetic complications. Research implications and future perspectives were also discussed.

【 授权许可】

Free