Peptide dendrimers with designer core for directed self-assembly

TETRAHEDRON

卷:71

Article

Verma, Ram P.¹  Shandilya, Ashutosh¹  Haridas, V.¹ 

[1] Indian Inst Technol, Dept Chem, New Delhi 110016, India

关键词: Peptide;    Dendrimer;    Click reaction;    Triazole;    Urea;   

DOI  :  10.1016/j.tet.2015.09.043

来源: Elsevier

【 摘 要 】

A series of designer peptide dendrimers with urea and urea-triazole cores were synthesized. Urea cored dendrimers assembled into fibrillar morphology, while dendrimers with urea-triazole core assembled into vesicular morphology. The core-dependent self-assembly behavior is studied by ultramicroscopy, Xray crystallography and supported by molecular dynamics simulation. (C) 2015 Elsevier Ltd. All rights reserved.

【 授权许可】

Free