Gold(I)-catalyzed rearrangement of alkynylaziridine indoles for the synthesis of spiro-tetrahydro-β-carbolines

TETRAHEDRON

卷:70

Article

Yang, Yan-Fang¹  Li, Lian-Hua¹  He, Yu-Tao¹  Luo, Jian-Yi¹  Liang, Yong-Min^1,2 

[1] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Solid Lubricat, Beijing 100864, Peoples R China

关键词: Gold;    Rearrangement;    Aminoallene;    Cyclization;    Tetrahydro-beta-carboline;   

DOI  :  10.1016/j.tet.2013.11.084

来源: Elsevier

【 摘 要 】

Functionalized spiro-tetrahydro-beta-carbolines were formed by an efficient gold(I)-catalyzed rearrangement reaction of alkynylaziridine indoles. The reaction involved a Friedel-Crafts type intramolecular reaction of alkynylaziridine indoles, following by hydroamination of aminoallene intermediate. (C) 2013 The Authors. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

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