Date-rape evidence through fast determination of γ-butyrolactone in adulterated beverages

TALANTA

卷:232

Article

Gallart-Mateu, D.¹  de la Guardia, M.¹  Garrigues, S.¹ 

[1] Univ Valencia, Dept Analyt Chem, Jeroni Munoz Bldg,50th Dr Moliner St, Valencia 46100, Spain

关键词: gamma-butyrolactone;    Beverages;    FTIR;    Surreptitious drug administration;    Forensic analysis;    Rape;    Sexual abuse;    Chemical submission;   

DOI  :  10.1016/j.talanta.2021.122387

来源: Elsevier

【 摘 要 】

An infrared spectroscopy (IR) based methodology has been developed to determine gamma-butyrolactone (GBL) in adulterated beverages. The proposed method permits the direct screening of GBL in beverages and involves a minimum sample treatment requiring less than 2 min for quantitative determination of GBL. Sensitivity of IR method was improved by using liquid-liquid extraction (LLE) providing detection limits of 0.023 mg g(-1). Accuracy of the proposed methodology was evaluated through the analysis of soft beverages and alcoholic cocktails spiked with GBL at concentration levels ranging from 0.075 to 10 mg g(-1) providing recovery values from 91 to 100%. GBL was determined in twelve blind-spiked beverages, including from mineral water to wine and cocktails. Results obtained were statistically comparable to those provided by a liquid chromatography (LC) reference methodology and consistent with the spiked values. Therefore, the use of LLE-FTIR allowed a simple, sensitive and quantitative determination of GBL in soft beverages and alcoholic cocktails, thus evidencing its use for sex submission intention.

【 授权许可】

Free