Three-dimensional hybrid graphene/nickel electrodes on zinc oxide nanorod arrays as non-enzymatic glucose biosensors

SENSORS AND ACTUATORS B-CHEMICAL

卷:251

Article

Mazaheri, Mozhdeh¹  Aashuri, Hossein¹  Simchi, Abdolreza^1,2 

[1] Sharif Univ Technol, Dept Mat Sci & Engn, Azadi Ave,POB 11365-9466, Tehran, Iran

[2] Sharif Univ Technol, Inst Nanosci & Nanotechnol, Azadi Ave,POB 11365-9466, Tehran, Iran

关键词: Biosensor;    Glucose;    Graphene;    Nickel nanoparticle;    Zinc oxide nanorod;    Electrochemistry;   

DOI  :  10.1016/j.snb.2017.05.062

来源: Elsevier

【 摘 要 】

We present a novel hybrid electrode based on reduced graphene oxide/nickel/zinc oxide heterostructures. The sensor was fabricated by template-free hydrothermal growth of ZnO nanorod arrays on conductive glass substrates (FTO) followed by conformal electrodeposition of nickel nanoparticles with an average size of 18 nm. Then, in-situ reduction and electrophoretic deposition of graphene oxide (GO) nanosheets on the structured ZnO/Ni electrode was performed. The prepared three-dimensional nanostructure exhibited fast electrocatalytic response (<3 s) towards glucose oxidation due to the large surface area and high electro-activity. The prepared biosensor possessed a wide linear range over 0.5 mu M-1.11 mM, a low detection limit of 0.15 mu M at signal/noise ratio (S/N) of 3, and a sensitivity of 2030 mu Acm(-2) mM(-1). Therefore, the performance of the sensor regarding the detection limit and sensitivity is better than many other electrodes utilized for non-enzymatic glucose detection. No interference from different electroactive substances such as uric acid and ascorbic acid is also noticed. The potential application of the 3D hybrid biosensors for detection of glucose in real human serum samples is shown. This novel structured electrode holds great promise for the development of biosensors and other electrochemical devices. (C) 2017 Elsevier B.V. All rights reserved.

【 授权许可】

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