Predictors of reported influenza vaccination in HIV-infected women in the United States, 2006-2007 and 2007-2008 seasons

PREVENTIVE MEDICINE

卷:50

Article

Althoff, Keri N.¹  Anastos, Kathryn^2,3,4  Nelson, Kenrad E.¹  Celentano, David D.¹  Sharp, Gerald B.⁵  Greenblatt, Ruth M.^6,7,8  French, Audrey L.^9,10  Diamond, Don J.¹¹  Holman, Susan¹²  Young, Mary¹³  Gange, Stephen J.¹ 

[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA

[2] Montefiore Med Ctr, Dept Med, Bronx, NY 10467 USA

[3] Montefiore Med Ctr, Dept Epidemiol, Bronx, NY 10467 USA

[4] Albert Einstein Coll Med, Bronx, NY 10467 USA

[5] NIAID, NIH, Bethesda, MD 20892 USA

[6] Univ Calif San Francisco, Dept Clin Pharm, San Francisco, CA 94143 USA

[7] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA

[8] Univ Calif San Francisco, Dept Epidemiol, San Francisco, CA 94143 USA

[9] Rush Univ, Med Ctr, Chicago, IL 60612 USA

[10] John H Stroger Jr Hosp Cook Cty, Chicago, IL 60612 USA

[11] City Hope Natl Med Ctr, Beckman Res Inst, Duarte, CA 91010 USA

[12] Suny Downstate Med Ctr, Dept Med, Brooklyn, NY 11203 USA

[13] Georgetown Univ, Dept Med, Washington, DC 20007 USA

关键词: HIV/AIDS;    Highly active antiretroviral therapy;    Influenza vaccine;    Vaccine coverage;    Multi-center study;    Cohort study;    United States;    Adult;    Female;   

DOI  :  10.1016/j.ypmed.2010.03.007

来源: Elsevier

【 摘 要 】

Objective. To estimate the cumulative incidence of self-reported influenza vaccination (vaccination coverage) and investigate predictors in HIV-infected women. Methods. In an ongoing cohort study of HIV-infected women in five US cities, data from two influenza seasons (2006-2007 n = 1209 and 2007-2008 n = 1161) were used to estimate crude and adjusted prevalence ratios (aPR) and 95% confidence intervals ([.]) from Poisson regression with robust variance models using generalized estimating equations (GEE). Results. In our study, 55% and 57% of HIV-infected women reported vaccination during the 2006-2007 and 2007-2008 seasons, respectively. Using data from both seasons, older age, non-smoking status, CD4 T-lymphocyte (CD4) count >= 200 cells/mm(3), and reporting at least one recent healthcare visit was associated with increased vaccination coverage. In the 2007-2008 season, a belief in the protection of the vaccine (aPR = 1.38 [1.18, 1.61]) and influenza vaccination in the previous season (aPR = 1.66 [1.44, 1.91]) most strongly predicted vaccination status. Conclusion. Interventions to reach unvaccinated HIV-infected women should focus on changing beliefs about the effectiveness of influenza vaccination and target younger women, current smokers, those without recent healthcare visits, or a CD4 count <200 cells/mm(3). (C) 2010 Elsevier Inc. All rights reserved.

【 授权许可】

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