Performance analysis of a swept-source optical coherence tomography system with a quadrature interferometer and optical amplification

OPTICS COMMUNICATIONS

卷:284

Article

Mao, Youxin¹  Flueraru, Costel¹  Chang, Shoude¹  Popescu, Dan P.²  Sowa, Michael G.² 

[1] Natl Res Council Canada, Inst Microstruct Sci, Ottawa, ON K1A 0R6, Canada

[2] Natl Res Council Canada, Inst Biodiagnost, Winnipeg, MB R3B 1Y6, Canada

关键词: Optical coherence tomography;    Quadrature interferometer;    Semiconductor optical amplifier;    Medical;    Biological imaging;   

DOI  :  10.1016/j.optcom.2011.01.016

来源: Elsevier

【 摘 要 】

A performance analysis of signal to noise ratio for an optical coherence tomography system with quadrature detection and a semiconductor optical amplifier in the sample arm is discussed. The results are compared and discussed in relation to a conventional OCT system (without optical amplification). An increase of the signal to noise ratio up to 14 dB at a depth of 0.5 mm is obtained compared to the system without the optical amplifier. Overall, an improvement was demonstrated for signal coming from deeper regions within the samples. Arterial plaque from a myocardial infarction-prone Watanabe heritable hyperlipidemic (WHHLMI) rabbit is visualized and characterized using this system. Improvement of signal to noise ratio increases the penetration depth possible for OCT images, from 1 mm to 2 mm within the vessel wall of an artery. Preliminary results show that vulnerable plaque with fibrous cap, macrophage accumulations and calcification in the arterial tissue are measurable with this OCT system. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.

【 授权许可】

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