Theory of mind and social judgments in people at clinical high risk of psychosis

SCHIZOPHRENIA RESEARCH

卷:150

Article

Healey, Kristin M.¹  Penn, David L.¹  Perkins, Diana²  Woods, Scott W.³  Addington, Jean⁴ 

[1] Univ N Carolina, Dept Psychol, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Psychiat, Chapel Hill, NC 27599 USA

[3] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA

[4] Univ Calgary, Fac Med, Dept Psychiat, Calgary, AB, Canada

关键词: Clinical high risk;    Schizophrenia;    Social cognition;    Theory of mind;    Social judgments;    Longitudinal study;   

DOI  :  10.1016/j.schres.2013.08.038

来源: Elsevier

【 摘 要 】

Background: Social cognitive deficits are consistently reported in psychotic populations. Few studies have longitudinally investigated social cognition in clinical high-risk (CHR) populations. Aims: Longitudinally examine theory of mind (ToM) and social judgments in a CHR sample to investigate the stability of performance over time and potential ability to predict conversion to psychosis. Method: 147 CHR individuals and 85 help seeking controls (HSC) were assessed for up to 2 years; 28 participants developed psychosis across both groups. Generalized linear mixed models for repeated measures were used to examine change over time for ratings on the three social cognitive indices of ToM, trustworthiness, and approachability. Hierarchical regression was used to test whether social cognitive variables explain more variance in conversion than IQ. Results: CHR individuals showed a positive bias in approachability judgments over time compared to HSC. Baseline ToM performance significantly (p < .05) predicted later conversion beyond IQ scores. These results were attenuated when controlling for baseline symptom level. Conclusions: Although ToM deficits might predate conversion to psychosis, one must consider initial symptoms as well. Social judgments were not associated with conversion to schizophrenia. (C) 2013 Elsevier B. V. All rights reserved.

【 授权许可】

Free