Longitudinal changes in social cognition in individuals at clinical high risk for psychosis: An outcome based analysis

SCHIZOPHRENIA RESEARCH

卷:204

Article

Shakeel, M. K.¹  Lu, L.¹  Cannon, T. D.²  Cadenhead, K. S.³  Cornblatt, B. A.⁴  McGlashan, T. H.⁵  Perkins, D. O.⁶  Seidman, L. J.^7,8  Tsuang, M. T.^3,9  Woods, S. W.⁵  Walker, E. F.¹⁰  Mathalon, D. H.^11,12  Bearden, C. E.^13,14  Addington, J.¹ 

[1] Univ Calgary, Dept Psychiat, Hotchkiss Brain Inst, Calgary, AB, Canada

[2] Yale Univ, Dept Psychol, New Haven, CT USA

[3] Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA

[4] Zucker Hillside Hosp, Dept Psychiat, Queens, NY USA

[5] Yale Univ, Dept Psychiat, New Haven, CT 06520 USA

[6] Univ N Carolina, Dept Psychiat, Chapel Hill, NC 27515 USA

[7] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Dept Psychiat, Boston, MA 02115 USA

[8] Massachusetts Gen Hosp, Boston, MA USA

[9] Univ Calif San Diego, Inst Genom Med, La Jolla, CA 92093 USA

[10] Emory Univ, Dept Psychol, Atlanta, GA 30322 USA

[11] Univ Calif San Francisco, Dept Psychiat, San Francisco, CA USA

[12] Psychiat Serv, San Francisco, CA USA

[13] Univ Calif Los Angeles, Dept Psychiat, Los Angeles, CA USA

[14] Univ Calif Los Angeles, Dept Biobehav Sci & Psychol, Los Angeles, CA USA

关键词: Social cognition;    Theory of mind;    Social perception;    Emotion perception;    Clinical high risk;    Psychosis;   

DOI  :  10.1016/j.schres.2018.08.032

来源: Elsevier

【 摘 要 】

Social cognition deficits have been observed in individuals at clinical high risk (CHR) for psychosis. Longitudinal change in social cognition were analyzed in CHR individuals from the North American Prodrome Longitudinal Study (NAPLS2) based on outcome at 24 months. Individuals (n = 359) were classified into remission, symptomatic, prodromal progression and transition to psychosis (CHR-T) groups. Social cognition was assessed using theory of mind, emotion perception, and social perception tasks. There were no differences at baseline or 24 months between the groups on social cognition. Non-transition groups improved significantly over time on social cognition, but CHR-T did not show this effect. (C) 2018 Elsevier B.V. All rights reserved.

【 授权许可】

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