Implantation of fresh and thawed-warmed embryos in single embryo transfer cycles: interpreting the initial beta-HCG

REPRODUCTIVE BIOMEDICINE ONLINE

卷:30

Article

Sites, Cynthia K.¹  St Marie, Peter¹  Rahil, Tayyab¹ 

[1] Tufts Univ, Sch Med, Baystate Med Ctr, Dept Obstet & Gynecol, Springfield, MA 01199 USA

关键词: blastocyst;    cryopreservation;    embryos;    single embryo transfer;    vitrification;    beta hCG;   

DOI  :  10.1016/j.rbmo.2014.12.003

来源: Elsevier

【 摘 要 】

Little is known about the effects of human embryo cryopreservation on developmental potential. Initial beta-HCG, indicating embryo implantation, was measured in 322 single embryo transfer cycles (246 fresh and 76 thawed-warmed). Median initial beta-HCG was higher for fresh compared with thawed-warmed transfers (126 versus 100 mIU/ml; P = 0.04). Blastocyst slow cooling resulted in a lower initial beta-HCG compared with vitrification (P = 0.01). Live birth rates were lower for blastocyst slow cooling (25%) compared with vitrification (71%) and fresh transfer (70%). We conclude that cryopreservation may impair an embryo's ability to produce beta-HCG, but that vitrification does not impair developmental potential. (C) 2014 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

【 授权许可】

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