Dissociation between recognition and recall in developmental amnesia

NEUROPSYCHOLOGIA

卷:47

Article; Proceedings Paper

Adlam, Anna-Lynne R.¹  Malloy, Megan²  Mishkin, Mortimer²  Vargha-Khadem, Faraneh¹ 

[1] UCL, Inst Child Hlth, Dev Cognit Neurosci Unit, London WC1N 1EH, England

[2] NIMH, Cognit Neurosci Sect, Bethesda, MD 20892 USA

关键词: Hippocampus;    Hypoxia;    Familiarity;    Recollection;    Doors and People test;   

DOI  :  10.1016/j.neuropsychologia.2009.01.038

来源: Elsevier

【 摘 要 】

Developmental amnesia (DA) is a memory disorder due to hypoxia/ischaemia-induced damage to the hippocampus early in life. To test the hypothesis that this disorder is associated with a disproportionate impairment in recall vis-a-vis recognition, we examined a group of 10 patients with DA on the Doors and People test, which affords a quantitative comparison between measures of the two memory processes. The results supported the hypothesis in that the patients showed a sharp, though not complete, recall-recognition dissociation, exhibiting impairment on both measures relative to their matched controls, but with a far greater loss in recall than in recognition. Whether their relatively spared recognition ability is due to restriction of their medial temporal lobe damage to the hippocampus or whether it is due instead to their early age at injury is still uncertain. (C) 2009 Elsevier Ltd. All rights reserved.

【 授权许可】

Free