期刊论文详细信息
NEUROPSYCHOLOGIA 卷:91
The effects of healthy aging, amnestic mild cognitive impairment, and Alzheimer's disease on recollection, familiarity and false recognition, estimated by an associative process-dissociation recognition procedure
Article
Pitarque, Alfonso1  Melendez, Juan C.1  Sales, Alicia1  Mayordomo, Teresa1  Satorres, Encar1  Escudero, Joaquin2  Algarabel, Salvador1 
[1] Univ Valencia, E-46003 Valencia, Spain
[2] Gen Hosp, Dept Neurol, Valencia, Spain
关键词: Familiarity;    Recollection;    False recognition;    Cognitive impairment;    Alzheimer's disease;   
DOI  :  10.1016/j.neuropsychologia.2016.07.010
来源: Elsevier
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【 摘 要 】

Given the uneven experimental results in the literature regarding whether or not familiarity declines with healthy aging and cognitive impairment, we compare four samples (healthy young people, healthy older people, older people with amnestic mild cognitive impairment - aMCI -, and older people with Alzheimer's disease AD) on an associative recognition task, which, following the logic of the process dissociation procedure, allowed us to obtain corrected estimates of recollection, familiarity and false recognition. The results show that familiarity does not decline with healthy aging, but it does with cognitive impairment, whereas false recognition increases with healthy aging, but declines significantly with cognitive impairment. These results support the idea that the deficits detected in recollection, familiarity, or false recognition in older people could be used as early prodromal markers of cognitive impairment. (C) 2016 Elsevier Ltd. All rights reserved.

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