Study on cognitive impairment in diabetic rats by different behavioral experiments

1st International Global on Renewable Energy and Development

Yu-Bin, Ji^1,2 ; Zeng-Yi, Li^1,2 ; Guo-Song, Xin^1,2 ; Chi, Wei^1,2 ; Hong-Jian, Zhu^1,2

Life Sci. and Environ. Science Research Center of Harbin University of Commerce

Heilongjiang Harbin, 150076, China^1

Natl. Ministry of Education Anti-Tumor Natural Drug Engineering Research Center

Heilongjiang Harbin, Life Sci. and Environ. Science Research Center of Harbin University of Commerce

Heilongjiang Harbin, 150076, China^2

关键词: Behavior evaluations;    Behavioral experiment;    Blank control group;    Cognitive impairment;    Diabetic rats;    Learning and memory;    Object recognition tests;    Retention time;   

Others  :  https://iopscience.iop.org/article/10.1088/1755-1315/100/1/012050/pdf
DOI  :  10.1088/1755-1315/100/1/012050

来源: IOP

【 摘 要 】

Object recognition test and Y maze test are widely used in learning and memory behavior evaluation techniques and methods. It was found that in the new object recognition experiment, the diabetic rats did more slowly than the normal rats in the discrimination of the old and new objects, and the learning and memory of the rats in the diabetic rats were injured. And the ratio of retention time and the number of errors in the Y maze test was much higher than that in the blank control group. These two methods can reflect the cognitive impairment in diabetic rats.