Frontoparietal network and neuropsychological measures in typically developing children

NEUROPSYCHOLOGIA

卷:159

Article

Solis, Isabel^1,2  Janowich, Jacki^1,2  Candelaria-Cook, Felicha²  Collishaw, William²  Wang, Yu-Ping³  Wilson, Tony W.⁴  Calhoun, Vince D.^2,5,6  Ciesielski, Kristina R. T.^1,7  Stephen, Julia M.² 

[1] Univ New Mexico, Dept Psychol, 2001 Redondo S Dr, Albuquerque, NM 87106 USA

[2] Mind Res Network & Lovelace Biomed & Environm Res, 1101 Yale Blvd NE, Albuquerque, NM 87106 USA

[3] Tulane Univ, Dept Biomed Engn, 6823 St Charles Ave, New Orleans, LA 70118 USA

[4] Univ Nebraska Med Ctr, Nebraska Med Ctr 988440, Dept Neurol Sci, Omaha, NE 68198 USA

[5] Univ New Mexico, Dept Elect & Comp Engn, 498 Terrace St NE, Albuquerque, NM 87106 USA

[6] Emory Univ, Georgia State Univ, Triinst Ctr Translat Res Neuroimaging & Data Sci, Georgia Inst Technol, 33 Glimer St SE, Atlanta, GA 30303 USA

[7] Harvard Med Sch, MGH MIT AA Martinos Ctr Biomed Imaging, Dept Radiol, 149 Thirteenth St,Suite 2301, Charlestown, MA 02129 USA

关键词: Magnetoencephalography;    Resting-state;    Frontoparietal network;    Neurodevelopment;   

DOI  :  10.1016/j.neuropsychologia.2021.107914

来源: Elsevier

【 摘 要 】

Resting-state activity has been used to gain a broader understanding of typical and aberrant developmental changes. However, the developmental trajectory of resting-state activity in relation to cognitive performance has not been studied in detail. The present study assessed spectral characteristics of theta (5-8 Hz) and alpha (9-13 Hz) frequency bands during resting-state in a priori selected regions of the frontoparietal network (FPN). We also examined the relationship between resting-state activity and cognitive performance in typically developing children. We hypothesized that older children and children with high attentional scores would have higher parietal alpha activity and frontal theta activity while at rest compared to young children and those with lower attentional scores. MEG data were collected in 65 typically developing children, ages 9-14 years, as part of the Developmental Chronnecto-Genomics study. Resting-state data were collected during eyes open and eyes closed for 5 min. Participants completed the NIH Toolbox Flanker Inhibitory Control (FICA) and Attention Test and Dimensional Change Card Sort Test (DCCS) to assess top-down attentional control. Spectral power density was used to characterize the FPN. We found during eyes open and eyes closed, all participants had higher theta and alpha power in parietal regions relative to frontal regions. The group with high attentional scores had higher alpha power during resting-state eyes closed compared to those with low attentional scores. However, there were no significant differences between age groups, suggesting changes in the maturation of neural oscillations in theta and alpha are not evident among children in the 9-14-year age range.

【 授权许可】

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