A unique whole-head Magnetoencephalography (MEG) system incorporating a superconducting imaging surface (SIS) has been designed and built at Los Alamos with the goal of dramatically improving source localization accuracy while mitigating limitations of current systems (e.g. low signal-to-noise, cost, bulk). Magnetoencephalography (MEG) measures the weak magnetic fields emanating from the brain as a direct consequence of the neuronal currents resulting from brain function. The extraordinarily weak magnetic fields are measured by an array of SQUID (Superconducting Quantum Interference Device) sensors. The position and vector characteristics of these neuronal sources can be estimated from the inverse solution of the field distribution at the surface of the head. In addition, MEG temporal resolution is unsurpassed by any other method currently used for brain imaging. Although MEG source reconstruction is limited by solutions of the electromagnetic inverse problem, constraints used for source localization produce reliable results.