Structural analysis and antioxidant activity of the glycoside from Imperial Chrysanthemum

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

卷:28

Article

Zhu, Zhen-Yuan¹  Pan, Li-Chao¹  Yun-Tang¹  Zhang, Yong-min² 

[1] Tianjin Univ Sci & Technol, Coll Food Sci & Biotechnol, Key Lab Food Nutr & Safety, Minist Educ, Tianjin 300457, Peoples R China

[2] Univ Pierre & Marie Curie Paris 6, Inst Parisien Chim Mol UMR CNRS 7201, 4 Pl Jussieu, F-75005 Paris, France

关键词: Imperial Chrysanthemum glucoside;    Isolation and purification;    Antioxidant;    Molecular structure;   

DOI  :  10.1016/j.bmcl.2018.03.059

来源: Elsevier

【 摘 要 】

A new glycoside, named as CG-1, was separated from Imperial Chrysanthemum with silica gel column chromatography. The purity was detected by TLC and HPLC. The crystal shape of CG-1 was consisting of a quadrangular and two rectangular pyramids. The analysis of DSC and TGA showed that the melting point of CG-1 crystal was 150.22 degrees C and had good thermal stability. The monosaccharide conformation analysis showed that it was D-glucose. The structure characteristics were compared by FT-IR, NMR spectroscopy and LC-MS and a molecular structure has been deduced which consistent with spectroscopic results. In vitro antioxidant results suggested that the glycoside extracted from Imperial Chrysanthemum could be effectively employed as natural antioxidant in health or functional food. This work is of significance to keep the antioxidant activity in the processing and application of Imperial Chrysanthemum. (C) 2018 Elsevier Ltd. All rights reserved.

【 授权许可】

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