Organelle-selective energy transfer: A fluorescent indicator of intracellular environment

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

卷:21

Article

Loudet, Aurore¹  Ueno, Yuichiro¹  Wu, Liangxing¹  Jose, Jiney¹  Barhoumi, Rola²  Burghardt, Robert²  Burgess, Kevin¹ 

[1] Texas A&M Univ, Dept Chem, College Stn, TX 77842 USA

[2] Texas A&M Univ, Dept Vet Integrat Biosci, College Stn, TX 77843 USA

关键词: Fluorescent probes;    Cell imaging;    Energy transfer;    Organelle-selective;    Confocal microscopy;   

DOI  :  10.1016/j.bmcl.2011.01.040

来源: Elsevier

【 摘 要 】

A dye cassette fluoresces green (ca 520 nm) in the cytoplasm, endoplasmic reticulum (ER), and lysosomes, but red in mitochondria, that is, it illustrates 'organelle specific energy transfer'. This phenomenon may open new horizons in intracellular imaging. (C) 2011 Elsevier Ltd. All rights reserved.

【 授权许可】

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