The functional connectivity between the locust leg pattern generators and the subesophageal ganglion higher motor center

NEUROSCIENCE LETTERS

卷:692

Article

Knebel, Daniel^1,2  Rillich, Jan^1,3  Nadler, Leonard⁴  Pflueger, Hans-Joachim⁴  Ayali, Amir^1,2 

[1] Tel Aviv Univ, Sch Zool, POB 39040, IL-6997801 Tel Aviv, Israel

[2] Tel Aviv Univ, Sagol Sch Neurosci, Tel Aviv, Israel

[3] Univ Leipzig, Inst Biol, Leipzig, Germany

[4] Freie Unversitat Berlin, Inst Neurobiol, Berlin, Germany

关键词: Locomotion;    Locust;    Insect;    Subesophageal ganglion (SEG);    Central pattern generator (CPG);    Intersegmental coordination;   

DOI  :  10.1016/j.neulet.2018.10.060

来源: Elsevier

【 摘 要 】

Higher motor centers and central pattern generators (CPGs) interact in the control of coordinated leg movements during locomotion throughout the animal kingdom. The subesophageal ganglion (SEG) is one of the insect head ganglia reported to have a role in the control of walking behavior. Here we explored the functional relations between the SEG and the thoracic leg CPGs in the desert locust. Backfill staining revealed about 300 SEG descending interneurons (DINs) altogether. Recordings from an in-vitro isolated chain of thoracic ganglia, with intact or severed connections to the SEG, during pharmacological activation were used to determine how the SEG affects the centrally generated motor output to the legs. The SEG was demonstrated to both activate leg CPGs and synchronize their bilateral activity. The role of the SEG in insect locomotion is discussed in light of these findings.

【 授权许可】

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