Emerging fractal patterns in a real 3D cerebral aneurysm

JOURNAL OF THEORETICAL BIOLOGY

卷:368

Article

Zavodszky, Gabor¹  Karolyi, Gyoergy²  Paal, Gyoergy¹ 

[1] Budapest Univ Technol & Econ, Fac Mech Engn, Dept Hydrodynam Syst, H-1111 Budapest, Hungary

[2] Budapest Univ Technol & Econ, Inst Nucl Tech, H-1111 Budapest, Hungary

关键词: Chaotic advection;    CFD;    Information dimension;   

DOI  :  10.1016/j.jtbi.2015.01.004

来源: Elsevier

【 摘 要 】

The behaviour of biological fluid flows is often investigated in medical practice to draw conclusions on the physiological or pathological conditions of the considered organs. One area where such investigations are proven to be useful is the flow-related formation and growth of different pathologic malformations of the cerebro-vascular system. In this work, a detailed study is presented on the effect of a cerebral aneurysm on blood transport inside a human brain artery segment. This malformation causes strong flow instabilities that drives the flow system towards chaotic behaviour. The emerging fractal structure and some of its measurable properties have been explored using a method that makes the measurement of these properties feasible even in complicated large three dimensional data sets. We find that, from the investigated chaos parameters, the information dimension turns out to be the most reliable parameter to characterise chaotic advection in the vicinity of the aneurysm sac. We propose that properties of chaotic mixing close to aneurysms might be relevant for the condition of this pathologic malformation. (C) 2015 Elsevier Ltd. All rights reserved.

【 授权许可】

Free