Selective recognition and electrochemical sensing of dopamine using a ferrocene-based heteroditopic receptor

TETRAHEDRON LETTERS

卷:59

Article

Miyaji, Hidekazu¹  Komoda, Haruka¹  Goto, Keisuke¹  Fujimoto, Junko¹  Kiriyama, Naoaki¹  Tucker, James H. R.² 

[1] Gifu Univ, Dept Chem & Biomol Sci, Fac Engn, 1-1 Yanagido, Gifu 5011193, Japan

[2] Univ Birmingham, Sch Chem, Birmingham B15 2TT, W Midlands, England

关键词: Electrochemical molecular sensor;    Dopamine;    Ferrocene;    Boronic acid;    Crown ether;   

DOI  :  10.1016/j.tetlet.2018.09.026

来源: Elsevier

【 摘 要 】

A redox-active ferrocene-based heteroditopic receptor bearing a boronic acid (as a catechol recognition site) and a benzo-18-crown-6-ether unit (as an ammonium ion recognition site) was synthesized. A 1:1 ditopic complex with dopamine was evidenced by mass spectrometry and NMR spectroscopy. Cyclic voltammetry measurements on the receptor in the presence of a series of organic guest species demonstrated the successful electrochemical sensing of dopamine through a distinct change in the ferrocene-centred redox-couple upon complex formation. (C) 2018 Elsevier Ltd. All rights reserved.

【 授权许可】

Free