Combining ferrocene, thiophene and a boronic acid: a hybrid ligand for reagentless electrochemical sensing of cis-diols

TETRAHEDRON LETTERS

卷:55

Article

Lacina, Karel¹  Konhefr, Martin²  Novotny, Jan¹  Potesil, David¹  Zdrahal, Zbynek¹  Skladal, Petr^1,2 

[1] Masaryk Univ, CEITEC, Brno 62500, Czech Republic

[2] Masaryk Univ, Fac Sci, Dept Biochem, Brno 62500, Czech Republic

关键词: Boronic acid;    Ferrocene;    Thiophene;    Reagentless sensing;    cis-Diols;   

DOI  :  10.1016/j.tetlet.2014.04.036

来源: Elsevier

【 摘 要 】

A redox-active affinity ligand suitable for reagentless sensing of cis-diols was synthesised and characterised. 4-[(Ferrocenylamino)methyl]thiophene-3-boronic acid (FcTBA) was allowed to interact with the model cis-diol, sorbitol. A discrete, cathodic shift of the redox potential was observed upon interaction of FcTBA with sorbitol thus providing simultaneous differentiation between the free and bound forms of this sensor molecule. Similar behaviour was observed also for FcTBA co-immobilised with thiophene in a mixed self-assembled monolayer on a gold electrode. (C) 2014 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license

【 授权许可】

Free