N-Functionalised TsDPEN catalysts for asymmetric transfer hydrogenation; synthesis and applications

TETRAHEDRON LETTERS

卷:56

Article

Soni, Rina¹  Hall, Thomas H.¹  Morris, David J.¹  Clarkson, Guy J.¹  Owen, Matthew R.¹  Wills, Martin¹ 

[1] Univ Warwick, Dept Chem, Coventry CV4 7AL, W Midlands, England

关键词: Asymmetric;    Transfer;    Hydrogenation;    Ketone;    TsDPEN;    Alcohol;   

DOI  :  10.1016/j.tetlet.2015.09.135

来源: Elsevier

【 摘 要 】

A series of Ru(II)/arene complexes containing N-alkylated derivatives of TsDPEN were prepared and tested in the asymmetric transfer hydrogenation (ATH) of ketones. The results demonstrated that a wide variety of functionality were tolerated on the basic amine of the TsDPEN ligand, without significantly disrupting the ability of the catalyst to catalyse hydrogen transfer reactions. (C) 2015 Elsevier Ltd. All rights reserved.

【 授权许可】

Free