No relationship between left ventricular radial wall motion and longitudinal velocity and the extent and severity of noncompaction cardiomyopathy

Cardiovascular Ultrasound

Research

Marcel L Geleijnse¹  Maarten L Simoons¹  Osama I Soliman¹  Attila Nemes¹  Ron T van Domburg¹  Kadir Caliskan² 

[1] Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands;Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands;Throaxcenter, Room Bd577, Erasmus MC,'s-Gravendijkwal 230, 3015, Rotterdam, CE, The Netherlands;

关键词: Noncompaction cardiomyopathy;    LV function;    Heart failure;    Tissue doppler imaging;   

DOI  :  10.1186/1476-7120-10-9

 received in 2011-12-29, accepted in 2012-03-19,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundNoncompaction cardiomyopathy (NCCM) is characterized by a prominent trabecular meshwork and deep intertrabecular recesses. Although systolic dysfunction is common, limited information is available on differences in wall motion of the normal compacted and noncompacted segments. The purpose of this study was to assess radial wall motion and longitudinal wall velocity in patients with NCCM, according to the extent and severity of noncompaction.MethodsThe study comprised 29 patients in sinus rhythm (age 41 ± 15 years, 15 men), who fulfilled stringent diagnostic criteria for NCCM and compared to 29 age and gender matched healthy controls. Segmental radial wall motion of all compacted and noncompacted segments was assessed with the standard visual wall motion score index and longitudinal systolic (Sm) wall velocity with tissue Doppler imaging of the mitral annulus. For each LV wall a normalized Sm value was calculated. The extent and severity of NC in each LV segment was assessed both in a qualitative and quantitative manner.ResultsHeart failure was the primary clinical presentation in half of the patients. NCCM patients had a wall motion score index of 1.68 ± 0.43 and a normalized Sm of 82 ± 20%. The total and maximal noncompaction scores were not related to the wall motion score index and the normalized Sm. NCCM patients with and without heart failure had similar total and maximal noncompaction scores.ConclusionsIn NCCM patient's radial wall motion and longitudinal LV wall velocity is impaired but not related to the extent or severity of noncompaction.

【 授权许可】

CC BY   
© Caliskan et al; licensee BioMed Central Ltd. 2012