Detection and Assessment Using Positron Emission Tomography of Genetically Determined Defects in Myocardial Fatty Acid Utilization. Final report, 8/1/93-6/30/97.

Bergmann, S. R.

Technical Information Center Oak Ridge Tennessee

关键词: Diagnostic equipment;    Heart failure;    Medical equipment;    Fatty acid metabolism;    Carboxylic acids;   

RP-ID  :  DE2001760727

学科分类：工程和技术（综合）

美国|英语

来源: National Technical Reports Library

【 摘 要 】

An approach using positron emission tomography (PET) was developed, validated and used to measure myocardial fatty acid metabolism in patients with inherited forms of heart failure. Abnormalities were correlated with the severity of the clinical illness. The approach developed was also shown to identify abnormalities in myocardial fatty acid metabolism in some patients with acquired forms of heart failure. The PET technique thus permits identification of abnormal fatty acid metabolism and provides an approach to evaluate the efficacy of interventional strategies.