Detection heart failures (HF) biomarkers by proton transfer reaction - mass spectrometry and ion mobility spectrometry

1st International Telecommunication Conference "Advanced Micro- and Nanoelectronic Systems and Technologies"

无线电电子学

Shaltaeva, Y.R.^1 ; Vasilev, V.K.^1 ; Yakovlev, D.Y.^1 ; Kopylov, F Iu^2 ; Syrkin, A.L.^2 ; Chomakhidze, P Sh^2 ; Bykova, A.A.^2 ; Malinovskaya, L.K.^2 ; Skorokhod, A.I.^3

National Research Nuclear University, MEPhI (Moscow Engineering Physics Institute), Kashirskoe shosse 31, Moscow

115409, Russia^1

I.M. Sechenov First Moscow State Medical University, Trubetskaya st. 8-2, Moscow

119991, Russia^2

A.M.Obukhov Institute of Atmospheric Physics RAS, Pyzhevskii pereulok 3, Moscow

119017, Russia^3

关键词: Control groups;    Exhaled breaths;    Heart failure;    Ion mobility spectrometry;    Proton-transfer reaction mass spectrometries;   

Others  :  https://iopscience.iop.org/article/10.1088/1757-899X/151/1/012017/pdf
DOI  :  10.1088/1757-899X/151/1/012017

来源: IOP

【 摘 要 】

Exhaled breath contains 1% of volatile organic compounds. The concentration of individual biomarkers in hundreds of volatile organic compounds lies within the range ppm- ppb. In compare with control group the concentrations of acetone, acetic acid, ethanol, propylene biomarkers is significantly higher in HF-PEF group.