Novel pebbles in the mosaic of autoimmunity

BMC Medicine

Editorial

Nancy Agmon-Levin¹  Yehuda Shoenfeld²  Carlo Perricone³ 

[1] The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, 52621, Tel Hashomer, Israel;The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, 52621, Tel Hashomer, Israel;Incumbent of the Laura Schwarz-Kip Chair for Research of Autoimmune Diseases, Tel-Aviv University, Tel Aviv, Israel;The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, 52621, Tel Hashomer, Israel;Reumatologia, Dipartimento di Medicina Interna e Specialità Mediche, Sapienza Università di Roma, Rome, Italy;

关键词: Autoimmunity;    Autoantibodies;    Autoimmune/inflammatory syndrome induced by adjuvants (ASIA);    Systemic lupus erythematosus;    Vitamin D;    Adjuvant;   

DOI  :  10.1186/1741-7015-11-101

 received in 2013-03-28, accepted in 2013-04-02,  发布年份 2013

来源: Springer

【 摘 要 】

Almost 25 years ago, the concept of the ‘mosaic of autoimmunity’ was introduced to the scientific community, and since then this concept has continuously evolved, with new pebbles being added regularly. We are now looking at an era in which the players of autoimmunity have changed names and roles. In this issue of BMC Medicine, several aspects of autoimmunity have been addressed, suggesting that we are now at the forefront of autoimmunity science. Within the environmental factors generating autoimmunity are now included unsuspected molecules such as vitamin D and aluminum. Some adjuvants such as aluminum are recognized as causal factors in the development of the autoimmune response. An entirely new syndrome, the autoimmune/inflammatory syndrome induced by adjuvants (ASIA), has been recently described. This is the new wind blowing within the branches of autoimmunity, adding knowledge to physicians for helping patients with autoimmune disease.

【 授权许可】

Unknown   
© Perricone et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.