Trend of transfusion transmitted infections frequency in blood donors: provide a road map for its prevention and control

Journal of Translational Medicine

Research

Jabbar Khan¹  Sobia Attaullah²  Sanaullah Khan³ 

[1] Department of Biological Sciences, Gomal University, D.I.Khan, Pakistan;Department of Zoology, Islamia College Peshawar (A Public Sector University), University Campus, Jamrod Road, 25120, Peshawar, Khyber Pakhtunkhwa, Pakistan;Molecular Parasitology and Virology Laboratory, Department of Zoology, Kohat University of Science and Technology, 26000, Kohat, Khyber Pakhtunkhwa, Pakistan;

关键词: TTIs;    HBV;    HCV;    HIV;    Syphilis;    Blood donor;   

DOI  :  10.1186/1479-5876-10-20

 received in 2011-10-03, accepted in 2012-01-31,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundTransfusion transmitted infections create significant burden on health care system. Donor selection is of paramount importance because infected individuals serve as an asymptomatic reservoir and a potential source of transmission.MethodsA retrospective study was carried out in healthy blood donors in the Lady Reading Hospital Peshawar, Pakistan over a period of three and a half years i.e., from January 2008 to June 2011, to determine the prevalence of HBV, HCV, HIV and syphilis in order to provide information for relevant polices.ResultsOut of 1,27,828 sample of blood donors, recorded mean prevalence for HBs Ag, anti-HCV, anti-HIV and syphilis was 2.68%, 2.46%, 0.06% and 0.43%, respectively, with an increasing trend in frequencies of transfusion transmitted infections (TTIs).ConclusionsThis study reflects that blood transfusion is one of the leading risk factor of spread of the TTIs, which showed the need and importance of the mandatory screening of these infectious markers in blood donations.

【 授权许可】

CC BY   
© Attaullah et al; licensee BioMed Central Ltd. 2011