Parathyroid involvement in thyroid cancer: an unforeseen event

World Journal of Surgical Oncology

Research

Paschalia K Iliadou¹  Stylianos Mandanas¹  Maria Boudina¹  Lemonia Mathiopoulou¹  Periklis Mitsakis¹  Kalliopi Pazaitou-Panayiotou¹  Alexandra Chrisoulidou¹  Kosmas Manafis²  Nikolaos Flaris³ 

[1] Department of Endocrinology & Endocrine Oncology, Theagenio Cancer Hospital, 2 Al Simeonidi street, 54007, Thessaloniki, Greece;Pathology Department, General Hospital of Kavala, 65302, Kavala, Greece;Pathology Department, Hippokratio Hospital, Thessaloniki, Greece;

关键词: Metastasis;    Parathyroid;    Thyroid cancer;   

DOI  :  10.1186/1477-7819-10-121

 received in 2011-10-17, accepted in 2012-06-01,  发布年份 2012

来源: Springer

【 摘 要 】

BackgroundParathyroid metastatic disease from thyroid cancer has not been studied extensively, mainly due to the need for parathyroid preservation during thyroid surgery.MethodsWe reviewed files from 1,770 patients with thyroid cancer followed up in our department and 10 patients with parathyroid metastases (0.5%) were identified. Patient and tumor characteristics were recorded.ResultsSix out of ten patients had metastases from papillary thyroid cancer, three from follicular thyroid cancer and one from anaplastic thyroid cancer. In nine patients parathyroid infiltration from thyroid cancer was found in direct contact with the thyroid cancer, and in one patient metastatic foci were observed not in continuity with the thyroid cancer.ConclusionsParathyroid involvement, although infrequent, may occur in thyroid cancer independently of patient age and tumor size. The clinical significance of such event is not clear. The influence on disease outcome remains to be elucidated.

【 授权许可】

Unknown   
© Chrisoulidou et al.; licensee BioMed Central Ltd. 2012. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.