Parathyroid involvement in thyroid cancer: an unforeseen event

World Journal of Surgical Oncology

Kalliopi Pazaitou-Panayiotou³  Lemonia Mathiopoulou³  Maria Boudina³  Nikolaos Flaris²  Kosmas Manafis¹  Paschalia K Iliadou³  Periklis Mitsakis³  Stylianos Mandanas³  Alexandra Chrisoulidou³ 

[1] Pathology Department, General Hospital of Kavala, 65302, Kavala, Greece;Pathology Department, Hippokratio Hospital, Thessaloniki, Greece;Department of Endocrinology & Endocrine Oncology, Theagenio Cancer Hospital, 2 Al Simeonidi street, Thessaloniki, 54007, Greece

关键词: Thyroid cancer;    Parathyroid;    Metastasis;   

Others  :  827638
DOI  :  10.1186/1477-7819-10-121

 received in 2011-10-17, accepted in 2012-06-01,  发布年份 2012

【 摘 要 】

Background

Parathyroid metastatic disease from thyroid cancer has not been studied extensively, mainly due to the need for parathyroid preservation during thyroid surgery.

Methods

We reviewed files from 1,770 patients with thyroid cancer followed up in our department and 10 patients with parathyroid metastases (0.5%) were identified. Patient and tumor characteristics were recorded.

Results

Six out of ten patients had metastases from papillary thyroid cancer, three from follicular thyroid cancer and one from anaplastic thyroid cancer. In nine patients parathyroid infiltration from thyroid cancer was found in direct contact with the thyroid cancer, and in one patient metastatic foci were observed not in continuity with the thyroid cancer.

Conclusions

Parathyroid involvement, although infrequent, may occur in thyroid cancer independently of patient age and tumor size. The clinical significance of such event is not clear. The influence on disease outcome remains to be elucidated.

【 授权许可】

   
2012 Chrisoulidou et al.; licensee BioMed Central Ltd.

【 图 表 】

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