Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer

World Journal of Surgical Oncology

Research

Sang-Soo Kim¹  Seok-Man Son¹  In-Ju Kim¹  Yoon Se Lee²  Jin-Choon Lee³  Byung-Joo Lee³  Soo-Geun Wang³  Yun-Sung Lim³ 

[1] Department of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Ami-dong 1ga, Seo-gu, 602-739, Pusan, Republic of Korea;Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, 138-739, Songpa-gu, Seoul, Republic of Korea;Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, 1-10, Ami-dong, Seo-gu, 602-739, Pusan, Republic of Korea;

关键词: Papillary thyroid cancer;    Ultrasonography;    Cervical lymph nodes;    Metastasis;   

DOI  :  10.1186/1477-7819-12-273

 received in 2013-12-26, accepted in 2014-08-16,  发布年份 2014

来源: Springer

【 摘 要 】

BackgroundIn thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC).MethodsData on 220 patients with solitary MPTC who underwent total thyroidectomy and neck dissection between 2008 and 2009 were evaluated retrospectively. We classified the US findings according to the nature, shape, echogenicity, extent, margin, and calcification of the primary tumor and evaluated the correlations between these findings and those of LNM.ResultsHypoechogenicity (odds ratio = 2.331, P = 0.025) and marked hypoechogenicity (OR = 4.032, P = 0.016) of MPTC were risk factors for central LNM. All of the patients with lateral cervical LNM showed hypoechogenicity or marked hypoechogenicity. Hypoechogenicity (odds ratio = 5.349, P = 0.047) and other types of calcification (odds ratio = 2.495, P = 0.010) were significant risk factors for lateral cervical LNM.ConclusionsSpecific sonographic findings (hypoechogenicity or marked hypoechogenicity, and calcification) suggest LNM.

【 授权许可】

CC BY   
© Lee et al.; licensee BioMed Central Ltd. 2014