Ultrasonographic findings relating to lymph node metastasis in single micropapillary thyroid cancer

World Journal of Surgical Oncology

Byung-Joo Lee¹  In-Ju Kim³  Sang-Soo Kim³  Seok-Man Son³  Soo-Geun Wang¹  Jin-Choon Lee¹  Yun-Sung Lim¹  Yoon Se Lee² 

[1] Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University School of Medicine and Medical Research Institute, Pusan National University Hospital, 1-10, Ami-dong, Seo-gu, Pusan 602-739, Republic of Korea;Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 138-739, Republic of Korea;Department of Internal Medicine, Pusan National University School of Medicine and Medical Research Institute, Ami-dong 1ga, Seo-gu, Pusan 602-739, Republic of Korea

关键词: Metastasis;    Cervical lymph nodes;    Ultrasonography;    Papillary thyroid cancer;   

Others  :  1148202
DOI  :  10.1186/1477-7819-12-273

 received in 2013-12-26, accepted in 2014-08-16,  发布年份 2014

【 摘 要 】

Background

In thyroid cancer, preoperative ultrasonography (US) is performed to detect the primary tumor and lymph node metastasis (LNM), which are related to prognosis. This study examined the relationships between specific US findings and LNM in micropapillary thyroid cancer (MPTC).

Methods

Data on 220 patients with solitary MPTC who underwent total thyroidectomy and neck dissection between 2008 and 2009 were evaluated retrospectively. We classified the US findings according to the nature, shape, echogenicity, extent, margin, and calcification of the primary tumor and evaluated the correlations between these findings and those of LNM.

Results

Hypoechogenicity (odds ratio = 2.331, P = 0.025) and marked hypoechogenicity (OR = 4.032, P = 0.016) of MPTC were risk factors for central LNM. All of the patients with lateral cervical LNM showed hypoechogenicity or marked hypoechogenicity. Hypoechogenicity (odds ratio = 5.349, P = 0.047) and other types of calcification (odds ratio = 2.495, P = 0.010) were significant risk factors for lateral cervical LNM.

Conclusions

Specific sonographic findings (hypoechogenicity or marked hypoechogenicity, and calcification) suggest LNM.

【 授权许可】

   
2014 Lee et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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