期刊论文详细信息
World Journal of Surgical Oncology
Primary undifferentiated pleomorphic sarcoma of the breast in a young female: a case report
Case Report
Kaushik Saha1  Arpita Saha1  Banushree C. Srinivasamurthy2  Ambedkar Raj Kulandaivelu3 
[1] Department of Pathology, All India Institute of Medical Sciences, Sijua Village, Dumduma, Bhubaneswar, Orissa-17, India;Department of Pathology, All India Institute of Medical Sciences, Sijua Village, Dumduma, Bhubaneswar, Orissa-17, India;Present Address: Department of Pathology, Indira Gandhi Medical College, 605113, Puducherry, India;Department of Pathology, Chennai Medical College, Trichy, India;
关键词: Sarcoma;    Undifferentiated;    Breast;    Immunohistochemistry;    Diagnostic challenge;   
DOI  :  10.1186/s12957-016-0947-9
 received in 2016-04-14, accepted in 2016-07-13,  发布年份 2016
来源: Springer
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【 摘 要 】

BackgroundUndifferentiated pleomorphic sarcoma is a rare entity and requires extensive immunohistochemical markers to differentiate it from other tumors of the breast.Case presentationWe present a 29-year-old female with a left breast lump for 2 months. Initial diagnosis of malignant spindle cell tumor was done on core biopsy following which total mastectomy was done. After extensive sampling, on histology, highly pleomorphic spindle cells palisading the area of geographic necrosis with very high atypical mitosis were seen. As there was diagnostic difficulty, immunohistochemical antibody panel was used and diagnosis of undifferentiated pleomorphic sarcoma of the breast was made by exclusion.ConclusionsCore biopsy with immunostaining is possibly superior to FNA as an initial diagnostic modality for breast masses with atypical features.

【 授权许可】

CC BY   
© The Author(s). 2016

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