A comparison of Chinese and non-Chinese Canadian patients hospitalized with heart failure

BMC Cardiovascular Disorders

Research Article

Ching Lau¹  Maria Chiu²  Nicole K Van Dyke²  Laura C Maclagan²  Dennis T Ko³  Jack V Tu³  Douglas S Lee⁴  Baiju R Shah⁵  Darwin F Yeung⁶  Gordon W Moe⁷ 

[1] Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada;Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, ON, Canada;Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, ON, Canada;Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, ON, Canada;Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, ON, Canada;Division of Cardiology, University Health Network, Toronto, ON, Canada;Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, ON, Canada;Division of Endocrinology, Sunnybrook Health Sciences Centre, Toronto, ON, Canada;Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, ON, Canada;Faculty of Medicine, University of Toronto, Toronto, Canada;St. Michael’s Hospital, Toronto, ON, Canada;

关键词: Heart failure;    Hypertension;    Valvular heart disease;   

DOI  :  10.1186/1471-2261-13-114

 received in 2013-07-19, accepted in 2013-12-01,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundCanadians of Chinese descent, represent one of the fastest growing visible minority groups in Canada, (as well as the second largest), but relatively little is known about the clinical features of heart failure (HF) in Chinese-Canadian versus non-Chinese Canadian patients.MethodsWe conducted a population-based analysis of urban patients hospitalized in Ontario, Canada for the first time with a most responsible diagnosis of HF between April 1, 1995 and March 31, 2008. Among the 99,278 patients, 1,339 (1.3%) were classified as Chinese using a previously validated list of Chinese surnames. Through linkage to other administrative databases, we compared the clinical characteristics, pharmacological management, and outcomes of Chinese versus non-Chinese HF patients.ResultsIschemic heart disease was identified as the possible etiology of HF in a greater proportion of non-Chinese patients (47.7% vs. 35.3%; p < 0.001) whereas hypertension (26.1% vs. 16.1%; p < 0.001) and valvular heart disease (11.6% vs. 7.2%; p < 0.001) were relatively more common in Chinese patients. Chinese patients were prescribed angiotensin-converting enzyme (ACE) inhibitors less frequently (57.5% vs. 66.4%, p < 0.001) and angiotensin receptor blockers (ARBs) more frequently (17.4% vs. 8.9%, p < 0.001) compared to non-Chinese patients. They were also less likely to be adherent to ACE inhibitors over a 1-year follow up period. However, the 1-year case-fatality rates were comparable between the Chinese (31.7%) and non-Chinese (30.2%) subjects (p = 0.24).ConclusionThere are important differences in the causes and medical management of HF in Chinese and non-Chinese patients residing in Canada. Despite these differences, the long-term outcomes of HF patients were similar.

【 授权许可】

Unknown   
© Yeung et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.