期刊论文详细信息
Basic and Clinical Andrology | |
Cell-free and intracellular nucleic acids: new non-invasive biomarkers to explore male infertility | |
Review Article | |
Amaël Petiton1  Solenne Baillet1  Antoine Torre1  Anne Boissière2  Alice Ferrières-Hoa3  Samir Hamamah3  Tiffany Mullet3  Anna Gala3  | |
[1] Département de biologie de la reproduction, Hôpital Arnaud de Villeneuve, CHRU Montpellier, 371, avenue du Doyen-Gaston-Giraud, 34295, Montpellier, France;Unité INSERM U1203, Hôpital Saint Eloi, CHRU Montpellier, 80, avenue Fliche, 34295, Montpellier, France;Unité INSERM U1203, Hôpital Saint Eloi, CHRU Montpellier, 80, avenue Fliche, 34295, Montpellier, France;Département de biologie de la reproduction, Hôpital Arnaud de Villeneuve, CHRU Montpellier, 371, avenue du Doyen-Gaston-Giraud, 34295, Montpellier, France; | |
关键词: cf-DNA; cf-mRNA; miRNA; piRNA; Male infertility; Seminal plasma; biomarkers; cf-DNA; cf-mRNA; miRNA; piRNA; Infertilité masculine; Plasma séminal; Biomarqueurs; | |
DOI : 10.1186/s12610-017-0052-0 | |
received in 2016-12-06, accepted in 2017-03-09, 发布年份 2017 | |
来源: Springer | |
【 摘 要 】
Male infertility is a devastating problem that affects many couples worldwide. However, the molecular mechanisms and causes of idiopathic male infertility remain unclear. Circulating cell-free nucleic acids have an important role in human physiology and emerging evidence suggests that they play a role in male infertility. This review summarizes recent results on cell-free and intracellular nucleic acids in male infertility and discusses their potential use as biomarkers of male infertility in the clinical practice.
【 授权许可】
CC BY
© The Author(s). 2017
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202311105221903ZK.pdf | 411KB | download |
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