Prevalence of major cardiovascular risk factors and adverse risk profiles among three ethnic groups in the Xinjiang Uygur Autonomous Region, China

Lipids in Health and Disease

Research

Yang Xiang¹  Xiao-mei Li¹  Zhen-Yan Fu¹  Jing Tao¹  Zi-xiang Yu¹  Xiang Xie¹  Yi-ning Yang¹  Yi-tong Ma¹  Xiang Ma¹  You Chen¹  Fen Liu²  Bang-dang Chen² 

[1] Department of Cardiology, First Affiliated Hospital of Xinjiang Medical University, 830054, Urumqi, P.R. China;Xinjiang Key Laboratory of Cardiovascular Disease Research, 830054, Urumqi, P.R. China;

关键词: Cardiovascular disease;    Risk factors;    Disparities;    Ethnicity;    Epidemiology;   

DOI  :  10.1186/1476-511X-12-185

 received in 2013-10-23, accepted in 2013-12-11,  发布年份 2013

来源: Springer

【 摘 要 】

BackgroundPrevalence of cardiovascular disease (CVD) risk factors have been scarcely studied in Xinjiang, a multi-ethnic region.MethodsMulti-ethnic, cross-sectional cardiovascular risk survey study in Xinjiang, including individuals of Uygur (n = 4695), Han (n = 3717) and Kazakh (n = 3196) ethnicities, aged 35-74 years. Analyses involved 11,608 participants with complete data enrolled between October 2007 and March 2010.ResultsThere were differences in age-standardized prevalence of CVD risk factors between the three groups (all P < 0.001). Hypertension, obesity and smoking rates were higher among Kazakh (54.6%, 24.5%, and 35.8%, respectively). Dyslipidemia prevalence was higher among Uygur (54.3%), and diabetes prevalence was higher among Hans (7.1%). Age-standardized prevalence of adverse CVD risk profiles was different across different ethnicities. Compared with the Han participants, the Uygur and Kazakh had more CVD risk factors (P < 0.001). Compared with the Han participants, the adjusted odds ratios of 1, 2, and ≥3 risk factors profiles for Kazakh and Uygur participants were higher (all P < 0.001).ConclusionsThe present study showed the pervasive burden of CVD risk factors in all participant groups in the Xinjiang region. Three major ethnic groups living in Xinjiang had striking differences in the prevalence of major CVD risk factors and adverse risk profiles. Ethnic-specific strategies should be developed to prevent CVD in different ethnic groups, as well as to develop strategies to prevent future development of adverse CVD risk factors at a younger age.

【 授权许可】

Unknown   
© Tao et al.; licensee BioMed Central Ltd. 2013. This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.