Prevalence of paratuberculosis in cattle based on gross and microscopic lesions in Ethiopia

BMC Veterinary Research

Research

Balako Gumi¹  Aboma Zewude²  Gobena Ameni²  Temesgen Mohammed²  Gezahegne Mamo³  Asegedech Sirak⁴ 

[1] Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia;Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia;Department of Veterinary Medicine, College of Agriculture and Veterinary Medicine, United Arab Emirates University, Al Ain, United Arab Emirates;College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia;National Animal Health Diagnostic and Investigation Center, Sebeta, Ethiopia;

关键词: Paratuberculosis;    Prevalence;    Pathology;    Cattle;    Ethiopia;   

DOI  :  10.1186/s12917-023-03725-x

 received in 2022-11-04, accepted in 2023-09-08,  发布年份 2023

来源: Springer

【 摘 要 】

BackgroundParatuberculosis, caused by Mycobacterium avium subsp. paratuberculosis (MAP), is a chronic progressive granulomatous enteritis mainly affecting domestic and wild ruminants worldwide. Although paratuberculosis could be prevail in Ethiopia, there is a scarcity of epidemiological data on paratuberculosis in the country. Thus, this study was conducted to estimate the prevalence of paratuberculosis based on gross and microscopic lesions in cattle slaughtered at ELFORA Abattoir, central Ethiopia. Small intestines and associated lymph nodes of 400 apparently healthy cattle which were slaughtered at ELFORA export abattoir were examined for gross and microscopic lesions of paratuberculosis. The microscopic lesions were classified into four grades (I-IV) based on the type and number of cells infiltrated into the lesion. The prevalence of paratuberculosis was estimated on the basis of gross as well as microscopic lesion of paratuberculosis.ResultsThe prevalence of paratuberculosis was 11.25% (95% Confidence interval, CI = 0.083–0.148) on the basis of gross lesion. However, relatively lower prevalence (2.0%, 95% CI = 0.01, 0.039) was recorded based on microscopic lesion. The gross lesions were characterized by intestinal thickening, mucosal corrugations and enlargement of associated mesenteric lymph nodes. On the other hand, the microscopic lesions were characterized by granuloma of different grades ranging from grade I to grade III lesions.ConclusionsThe present study indicated the occurrence of paratuberculosis in cattle of Ethiopia based on the detection of gross and microscopic lesions consistent with the lesion of paratuberculosis. The result of this study could be used as baseline information for future studies on the epidemiology and economic significance of paratuberculosis.

【 授权许可】

CC BY   
© BioMed Central Ltd., part of Springer Nature 2023

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