Clinical, genetic, and pathological features of male pseudohermaphroditism in dog

Reproductive Biology and Endocrinology

Methodology

Enrico Bigliardi¹  Stefano Jottini¹  Anna Maria Cantoni¹  Benedetta Passeri¹  Lisa De Lorenzi²  Pietro Parma²  Peter Wohlsein³  Paolo Peressotti⁴ 

[1] Department of Animal Health, Faculty of Veterinary Medicine, Parma, Italy;Department of Animal Science, Faculty of Agronomy, Milan, Italy;Department of Pathology, University of Veterinary Medicine Hannover, Germany;Private Clinics, Parma, Italy;

关键词: Sertoli Cell;    Seminiferous Tubule;    Tunica Albuginea;    Leydig Cell Tumor;    Cremaster Muscle;   

DOI  :  10.1186/1477-7827-9-12

 received in 2010-09-05, accepted in 2011-01-21,  发布年份 2011

来源: Springer

【 摘 要 】

Male pseudohermaphroditism is a sex differentiation disorder in which the gonads are testes and the genital ducts are incompletely masculinized. An 8 years old dog with normal male karyotype was referred for examination of external genitalia abnormalities. Adjacent to the vulva subcutaneous undescended testes were observed. The histology of the gonads revealed a Leydig and Sertoli cell neoplasia. The contemporaneous presence of testicular tissue, vulva, male karyotype were compatible with a male pseudohermaphrodite (MPH) condition.

【 授权许可】

CC BY   
© Bigliardi et al; licensee BioMed Central Ltd. 2011