Opportunities and challenges in the development of Cutaneotrichosporon oleaginosus ATCC 20509 as a new cell factory for custom tailored microbial oils

Microbial Cell Factories

Review

Felix Bracharz¹  Norbert Mehlmer¹  Thomas Brück¹  Teun Beukhout² 

[1] Technische Universität München, Division of Industrial Biocatalysis, Lichtenbergstraße 4, 85748, Garching, Germany;Westerdijk Institute, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands;

关键词: Apiotrichum curvatum;    Trichosporon oleaginosus;    Cryptococcus curvatus;    Cutaneotrichosporon oleaginosus;    Oleaginous yeast;    Single cell oil;    Lipid;    Basidiomycete;   

DOI  :  10.1186/s12934-017-0791-9

 received in 2017-05-25, accepted in 2017-10-14,  发布年份 2017

来源: Springer

【 摘 要 】

Cutaneotrichosporon oleaginosus ATCC 20509, previously known as Trichosporon oleaginosus, Cryptococcus curvatus, Apiotrichum curvatum or Candida curvata D is an oleaginous yeast with several favorable qualities: it is fast growing, accumulates high amounts of lipid and has a very broad substrate spectrum. Its resistance to hydrolysis byproducts and genetic accessibility make it a promising cell factory for custom tailored microbial oils. However, literature about this organism is of varying degree of quality. Moreover, due to numerous changes of the species name, reports are highly scattered and poorly cited. This led to a poor integration of the findings into a unified body of knowledge. Particularly, errors in strain name usage and consequently citation are found even in most recent literature. To simplify future work, this review provides an overview of published studies and main findings regarding the metabolic capacities of C. oleaginosus.

【 授权许可】

CC BY   
© The Author(s) 2017